The Monday Night Football alternate stream hosted by former two-time Super Bowl champion, Super Bowl XLI MVP, and five-time NFL Most Valuable Player Peyton Manning, and his brother, two-time Super Bowl champion, and two-time Super Bowl MVP, Eli Manning, will broadcast on ESPN2 at 8:15 EDT/ 7:15 CDT.

For Dallas, this will be their chance to build momentum in the wake of Dak Prescott’s thumb fracture during a Week 1 loss to the Tampa Bay Buccaneers. Cowboys owner Jerry Jones didn’t exactly have good news about the quarterback’s future during an appearance on 105.3 The Fan on September 20:

In his place, Cooper Rush will start after leading the offense in a win against the Bengals in a Week 2 upset against the defending AFC Champions.

For the Giants, this will be a chance to move to 3-0 for the first time since their 2009 season, where they started off hot but finished at just 8-8. This is a hallmark of the down years during the Eli Manning era.

Saquon Barkley must overcome the ManningCast curse

Typically, ManningCast special guests who are still active in the NFL see things fall off the rails in the week that follows an appearance. However, Saquon Barkley, who was a Week 1 guest for the Seahawks’ upset of the Broncos, avoided that in Week 2 against the Carolina Panthers.

Perhaps the football gods were waiting for Barkley to be on the ManningCast himself to impose the curse on the Big Blue running back, who has amassed 236 yards and a rushing touchdown through their first two wins in this young 2022 NFL season.

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